With patients and the people who care for them at the center of all we do, we build connections across the healthcare industry. Together, we are the Surescripts Network Alliance.

Built to Enhance Prescribing and Transform Interactions between Clinicians, Pharmacists and Patients


Give healthcare professionals in all care settings safer and more efficient electronic prescription management.

Benefit Optimization

Deliver real-time, patient-specific benefit, price and therapeutic alternative information to the point of care.

Clinical Direct Messaging

Record Locator Exchange

Delivers relevant and timely patient data

In 2020, 84% of all prescriptions were delivered electronically through the Surescripts network.

Wide-reaching coverage

The Surescripts master patient index represents 324 million patients--98% of the U.S. population.

Promotes medication adherence

E-Prescribing is associated with up to a 20% increase in first-fill medication adherence when used with benefit information.

Lower costs

E-Prescribing improves administrative performance and clinical outcomes helping address $140-$240 billion in potential savings over 10 years.

Making an Impact on Patients Together

As the COVID-19 pandemic accelerates change across healthcare, the Surescripts Network Alliance is innovating to tackle our shared challenges and deliver better care.

Increasing Patient Safety

We’ve improved our network-wide Quality Index Score for electronic prescriptions more than 80% since 2016.

Lowering Costs

In several practice areas, prescribers who use Surescripts to find a less costly alternative save patients an average of $50 or more per prescription.

Ensuring Quality Care

In 2020, we helped 137,000 clinicians from 23,414 organizations nationwide quickly see where patients received care and locate medical records.

See Who Surescripts Connects

Locate E-Prescribing Pharmacies and Physicians